Photodynamic therapy triggered by spectral scanner CT: an efficient tool for cancer treatment



The University Claude Bernard Lyon 1 (UCBL) is the fifth largest French university, and the 1st one in the field of health, taking into account the number of students.  The UCBL student population is nearly 40 000, and it employs 2900 teachers/researchers and teachers, of which 700 are also hospital practitioners, as well as 1800 technical and administrative staff. The University has 73 state-funded research units working in three fields; health, the environment and material technologies. It is a multidisciplinary university specializing in both fundamental and applied research and as such it can boast more than 4415 internationally published articles and 44 patents per year.

Two Research Units of the University are involved in the present project:

CREATIS is a joint biomedical imaging research facility, from the University Claude Bernard Lyon1, INSA of Lyon, Centre National de la Recherche Scientifique (CNRS) and the Institut National de la Santé et de la Recherche Médicale (INSERM). CREATIS gathers together about 200 scientists from Computer Science, Engineering, Physics, and clinical investigators from Cardiology, Neurology, and Radiology. CREATIS researchers provide specialized expertise in image acquisition and image post-processing for different modalities such as CT, MRI, and US, with a focus on two fundamental problems, namely:

-        Identification of major health issues that can be addressed by imaging

-        Identification of theoretical barriers in biomedical imaging related to signal and image processing, modelling and numerical simulation.

Pr Philippe DOUEK is former Chairman of a consortium of 10 Departments of Radiology and Nuclear Medicine in Lyon Hospital (HCL), France, including 60 physicians and researchers, and 600 paramedical employees; equipment includes 10 CT, 7 MR, 1 PET-CT scanners, with an annual budget of 50 M€. As Professor of radiology, he is a teacher and researcher belonging to CREATIS (CNRS UMR 5220, INSERM U.630). He has more than 15 years of imaging research, with many multidisciplinary projects in this field, as well as international collaboration (NIH, UCSF). He has strong experience in coordination of preclinical and clinical projects in imaging research involving clinicians, basic science researchers; imaging companies and pharmaceutical companies (e.g. the only French national imagery cost effective study PHRC funded called CARMEDAS). Philippe Douek has been the coordinator of the H2020 project SPCCT.